Nasolacrimal duct obstruction secondary to lacrimal sac involvement by sebaceous carcinoma

Albert Wu , David S Curragh , Rebecca Morrow , Dinesh Selva & Garry Davis

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Malignant tumors of the eyelid in India: A multicenter, multizone study on clinicopathologic features and outcomes

Roshmi Gupta, Anirban Bhaduri, Savari Desai, Sima Das, Vikas Menon

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Malignant tumors of the eyelid – To err is human, to learn divine

Santosh G Honavar

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Management of recurrent sebaceous gland carcinoma

Lindsay A. McGrath, Zanna I. Currie, Hardeep Singh Mudhar, Jennifer H. Y. Tan & Sachin M. Salvi 

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Vimentin overexpression as a novel poor prognostic biomarker in eyelid sebaceous gland carcinoma

Mansi Bhardwaj, Seema Sen, Kunzang Chosdol, Sameer Bakhshi, Neelam Pushker, Anjana Sharma, Seema Kashyap, Mandeep S Bajaj, Vijay Kumar Singh

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Eyelid abscess masking underlying sebaceous cell carcinoma

Colin Bacorn, Esther Kim & Lily Koo Lin

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Human papillomavirus in ocular malignant tumours: a study from a tertiary eye care centre in North India

Sheetal Chauhan, Seema Sen, Neeta Singh, Anjana Sharma, Neelam Pushker, Seema Kashyap, Bhavna Chawla

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The present study aims to detect the presence of human papillomavirus (HPV) in ocular malignant tumours, including retinoblastoma, eyelid squamous cell carcinoma (SCC), and sebaceous gland carcinoma (SGC), in the North Indian population.



Prospective observational non randomized study.



In this study, 142 prospective cases of ocular malignant tumours (retinoblastoma, SGC, and SCC) were included.



HPV was detected by multiplex PCR using PGMY09/11 primers in 142 patients with ocular malignancies. This was followed by genotyping using linear array (reverse hybridization).



Of the 142 tumours studied, 72 were retinoblastoma, 30 SGC, and 40 SCC. The HPV genome was detected in 2.8% (4 of 142) of cases by multiplex PCR; all positive cases (4 of 40) were SCC. Genotyping revealed that all positives belonged to the high-risk HPV16 genotype. HPV-positive SCC patients had better disease-free survival. Retinoblastoma and SGC cases were negative for HPV.



Low prevalence of HPV in ocular malignancies was observed in this study. The HPV genome was detected only in ocular squamous cell carcinoma cases and these patients were associated with better prognosis. HPV may not have a role in retinoblastoma and SGC in the North Indian population.


Malignant eyelid tumors: Are intra-operative rapid frozen section and permanent section diagnoses of surgical margins concordant?

Swathi Kaliki, Sasi Pyda, Nupur Goel, Tarjani Vivek Dave, Milind N. Naik, Dilip K. Mishra

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Predictors of Local Recurrence for Eyelid Sebaceous Carcinoma Questionable Value of Routine Conjunctival Map Biopsies for Detection of Pagetoid Spread

Sa, Ho-Seok; Tetzlaff, Michael T.; Esmaeli, Bita

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The practice patterns in the management of sebaceous carcinoma of the eyelid in the Asia Pacific region

Janice J. C. Cheung, Bita Esmaeli, Stacey C. Lam, Tracey Kwok & Hunter K. L. Yuen

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