Leyngold, Ilya M.; Yen, Michael T.; Tian, James; Leyngold, Mark M.; Vora, Gargi K.; Weller, Christopher
Purpose: To describe a minimally invasive surgical technique and its clinical outcomes with the use of acellular nerve allograft to re-establish corneal sensibility in patients with neurotrophic keratopathy.
Methods: Acellular nerve allograft was coapted to an intact supraorbital, supratrochlear, or infraorbital nerve and transferred to the affected eye. Donor nerve pedicles were isolated through a transpalpebral or transconjunctival approach. Retrospective evaluation of preoperative and postoperative corneal sensibility, ocular surface, and best-corrected visual acuity was performed in all patients. Mean follow-up period was 6 months (range: 3–10 months).
Results: Corneal neurotization with acellular nerve allograft was successfully performed in 7 patients with restoration of corneal sensibility and corneal epithelial integrity. In vivo confocal microscopy demonstrated increased nerve density in corneal stroma at 4 months after surgery.
Conclusions: The use of acellular nerve allograft allows for a minimally invasive approach to successful corneal neurotization.
Leyngold, Ilya, M.D.; Weller, Christopher, M.D.; Leyngold, Mark, M.D.; Espana, Edgar, M.D.; Black, Kaelan, D., M.D.; Hall, Kathryn, L., M.D.; Tabor, Mark, M.D.
Purpose: The authors describe a cadaver feasibility study investigating a minimally invasive technique for corneal neurotization with the supraorbital nerve harvested endoscopically.
Methods: A cadaver study was performed to investigate the technical feasibility of corneal neurotization via endoscopic supraorbital nerve transfer to the corneoscleral limbus.
Results: Endoscopic corneal neurotization was successfully performed on each cadaveric hemiface.
Conclusion: The use of an endoscope allows for a minimally invasive approach to corneal neurotization with the supraorbital nerve.
Leyngold, Ilya; Weller, Christopher; Leyngold, Mark; Tabor, Mark
The authors describe a minimally invasive surgical technique to re-establish corneal sensibility in a patient with neurotrophic keratopathy with the supraorbital nerve harvested endoscopically.
Pedicled contralateral supraorbital nerve was harvested endoscopically through small eyelid crease and scalp incisions and transferred to the affected eye.
Endoscopic corneal neurotization was successfully performed with restoration of corneal sensibility and corneal epithelial integrity.
The use of an endoscope allows for a minimally invasive approach to successful corneal neurotization with the supraorbital nerve.