Squamous cell carcinoma of the lacrimal punctum: A rare presentation
Akshay Gopinathan Nair, Indumati Gopinathan, Vandana JainRead More
Ocular surface squamous neoplasia (OSSN) encompasses a variety of conjunctival and corneal epithelial tumors including dysplasia, carcinoma in situ, and invasive carcinoma. OSSN commonly affects the interpalpebral conjunctiva and typically arises from the nasal limbus as a solitary growth. It is generally believed that these tumor cells originate from dysfunctional limbal stem cells that have been altered by various mutagenic agents, such as UV radiation; however, these lesions can also be seen to extend across the limbus to involve the cornea. Rarely, OSSN may be seen to arise from atypical locations such as the palpebral conjunctiva.,, In addition, there have been documented cases of squamous cell carcinoma of the lacrimal sac and canaliculus presenting as punctal masses and canaliculitis as well.,, To the best of our knowledge, there has been no previous documented case of conjunctival squamous cell carcinoma presenting as an isolated peri-punctal mass with no involvement of the lacrimal sac. This study was adherent with the tenets of the Declaration of Helsinki.