Episcleral brachytherapy for retinoblastoma

Jose J Echegaray, Yahya A Al-Zahrani, Arun Singh

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Tumour size criteria for Group D and E eyes in the International Classification System for Retinoblastoma: effects on rates of globe salvage and high‐risk histopathologic features

Jonathan W. Kim, Sona N. Shah, Sarah Green, John O’Fee, Benita Tamrazi, Jesse L. Berry

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Secondary Prevention of Retinoblastoma Revisited

Sameh E. Soliman, Cynthia VandenHoven, Leslie D. MacKeen, Brenda L. Gallie

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Examinations under anaesthesia as a measure of disease burden in unilateral retinoblastoma: the London experience

Ido Didi Fabian, Vishal Shah, Noa Kapelushnik, Zishan Naeem, Zerrin Onadim, Elizabeth Price, Tanzina Chowdhury, Catriona Duncan, David Stansfield, Mandeep Sagoo, Maddy Ashwin Reddy

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Categories: BJO


Retinoblastoma vascular perfusion and intra‐arterial chemotherapy cycle requirements

Li‐Anne S. Lim MB BS Lauren A. Dalvin MD David Ancona‐Lezama MD Michael D. Yu BS Pascal Jabbour MD Carol L. Shields MD

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Human papillomavirus in ocular malignant tumours: a study from a tertiary eye care centre in North India

Sheetal Chauhan, Seema Sen, Neeta Singh, Anjana Sharma, Neelam Pushker, Seema Kashyap, Bhavna Chawla

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The present study aims to detect the presence of human papillomavirus (HPV) in ocular malignant tumours, including retinoblastoma, eyelid squamous cell carcinoma (SCC), and sebaceous gland carcinoma (SGC), in the North Indian population.



Prospective observational non randomized study.



In this study, 142 prospective cases of ocular malignant tumours (retinoblastoma, SGC, and SCC) were included.



HPV was detected by multiplex PCR using PGMY09/11 primers in 142 patients with ocular malignancies. This was followed by genotyping using linear array (reverse hybridization).



Of the 142 tumours studied, 72 were retinoblastoma, 30 SGC, and 40 SCC. The HPV genome was detected in 2.8% (4 of 142) of cases by multiplex PCR; all positive cases (4 of 40) were SCC. Genotyping revealed that all positives belonged to the high-risk HPV16 genotype. HPV-positive SCC patients had better disease-free survival. Retinoblastoma and SGC cases were negative for HPV.



Low prevalence of HPV in ocular malignancies was observed in this study. The HPV genome was detected only in ocular squamous cell carcinoma cases and these patients were associated with better prognosis. HPV may not have a role in retinoblastoma and SGC in the North Indian population.



Preservation of retinoblastoma group E eyes with neovascular glaucoma using intravenous chemotherapy: risk factors and outcomes

Raksha Rao, Santosh G Honavar, Vijayanand Palkonda Reddy

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Unilateral unifocal advanced intraocular retinoblastoma: is reasonable to adopt intra‐arterial chemotherapy as single therapeutic choice?

Sonia De Francesco, Sara Leonini, Paolo Galluzzi, Sandra Bracco, Paola Gennari, Anna Maria Pinto, Giovanni Neri, Matteo Barchitta, Alessandra Renieri, Doris Hadjistilianou

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Neonatal retinoblastoma: A study of five cases

Swathi Kaliki, Sai Divya Jajapuram

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Histopathologic findings after selective ophthalmic arterial injection of melphalan for retinoblastoma

Ho-Min Chen, Sherine Jue Ong, An-Ning Chao, Kuan-Lyin Liou, Shih-Ming Jung, Ling-Yuh Kao

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